Alzheimer's disease

 


Alzheimer's disease is a mental disorder that gradually damages memory and thinking skills and, ultimately, the ability to perform simple tasks. For most people with the disease - those with late-onset symptoms begin to appear in their 60s. Alzheimer's is a type of dementia that affects memory, thinking, and behavior. Symptoms eventually develop severe enough to interfere with daily activities. Understanding Alzheimer’s and dementia;  Alzheimer's is the most common cause of dementia, a common term for memory loss and other cognitive skills critical enough to disrupt daily life. Alzheimer's disease causes 60-80% of dementia cases.

Alzheimer's is not a normal part of aging. The most common risk factor is age, and most people with Alzheimer's age are 65 and older. Alzheimer’s disease is considered to be Alzheimer’s disease which starts in young people when it affects a person under 65 years of age. Early-onset can also be called Alzheimer’s onset. People with Alzheimer’s onset may be in the early stages, in the middle or late stage of the disease.

Alzheimer's disease gets worse over time. Alzheimer's disease is a progressive disease, in which symptoms of dementia gradually become worse over years. In its early stages, memory loss is minimal, but with Alzheimer's coming late, people lose the ability to continue the conversation and change their location. Alzheimer's is the sixth-leading cause of death in the United States. On average, a person with Alzheimer's disease lives 4 to 8 years after being diagnosed but can live for 20 years, depending on other factors.

Alzheimer's has no cure, but only one treatment - aducanumab (Aduhelm ™) - is the first treatment to show that removing amyloid, one of the symptoms of Alzheimer's disease, in the brain is likely to reduce dementia and function in diabetic adults. Alzheimer's. Other treatments can temporarily alleviate symptoms and improve the quality of life of those with Alzheimer's disease and their caregivers. Today, there is a worldwide effort to find better ways to treat the disease, delay its onset, and prevent further development. Symptoms of Alzheimer's; the first most common symptom of Alzheimer’s is difficulty remembering new information learned. Like all of our bodies, our brain changes as we grow older. Most of us end up experiencing slower thinking and occasional problems remembering certain things. However, severe memory loss, confusion, and other major changes in the way our brain works may be a sign that brain cells are failing. Alzheimer’s mutations usually begin in the part of the brain that affects learning. As Alzheimer’s progresses in the brain it leads to more serious symptoms, including confusion, mood swings, and behavioral changes; deep confusion about events, time, and place; baseless allegations about family, friends, and trained caregivers; severe memory loss and behavioral changes; and difficulty speaking, swallowing and walking. People who lose their memory or other symptoms of Alzheimer's may find it difficult to recognize that they have a problem. Symptoms of dementia may be more obvious to family members or friends. Anyone with symptoms such as dementia should see a doctor immediately. If you need help finding a doctor who can diagnose memory problems, your local Alzheimer's Association can help. Early diagnosis and interventions improve significantly, and treatment options and sources of support can improve quality of life. Alzheimer's and brain; very small changes in the brain begin long before the first symptoms of memory loss. The brain is made up of some 100 trillion nerve cells (neurons). Each nerve cell joins many others to form a network of connections. Nerve groups have special functions. Others are involved in thinking, reading, and remembering. Others help us to see, hear, and smell. To perform their function, the brain cells function as small cells. They get resources, generate energy, build resources and dispose of waste. Cells also process and store information and communicate with other cells. Keeping everything running smoothly requires a combination of a large amount of fuel and oxygen. Scientists believe that Alzheimer's disease prevents parts of the cell factory from working properly. They are not sure where the trouble starts. But like the real industry, backups and crashes in a single system cause problems in some areas. As the damage escalates, the cells lose their ability to function, and eventually they die, resulting in irreversible changes in the brain.

Role of plaque and tangles; two unusual structures called plaques and tangles are major culprits in damaging and killing nerve cells. Deposit plaque deposits of a protein called beta-amyloid (BAY-tuh AM-uh-loyd) form in the spaces between nerve cells. Twisted fiber tangles are another protein called tau (which has “wow”) formed inside cells. Three brain images, one with a few tangles, one with a medium junction, and one with a high degree of complexity. Although autopsy studies show that most people develop plaques and congestion as they grow older, those with Alzheimer's tend to grow more and more unpredictably. The pattern begins in important areas of memory before spreading to other regions. Scientists do not know exactly what role plaques and tangles play in Alzheimer's disease. Many experts believe that they are playing a key role in regulating the interaction of nerve cells and disrupting the processes that cells need to survive. Destruction and death of nerve cells result in memory loss, personality changes, problems with daily activities, and other symptoms of Alzheimer's disease.

What is the life expectancy of a person with Alzheimer's disease? The progression of Alzheimer's disease varies widely. On average, people with Alzheimer's disease live between 3 and 11 years after being diagnosed, but some survive 20 years or more.

Ten warning signs of Alzheimer”s: Loss of memory; one of the most common symptoms of dementia is forgetfulness of newly learned information. Although it is common to forget specific appointments, names, or phone numbers, those with dementia will often forget such things and not remember them later. Difficulty in performing routine tasks; people with dementia often find it difficult to complete the daily activities they are accustomed to and often do not think about how they are done. A person with Alzheimer's may be unaware of the steps to prepare food, use a treadmill, or engage in leisure activities for life. Language problems; everyone has a hard time finding the right word sometimes, but a person with Alzheimer's disease often forgets simple words or changes unfamiliar words, making his or her speech or writing difficult to understand. If someone with Alzheimer's can't get his toothbrush, for example, someone may ask for "that thing in my mouth." Misunderstanding time and place; it is common to forget the day of the week or your destination. But people with Alzheimer's disease can get lost in their path, forget where they are and how to get there, and not know how to get home. Bad or diminished judgment; no one always has perfect judgment. Those with Alzheimer’s may wear it regardless of the weather, wearing a few shirts or blouses on a warm day or very light clothing in the cold. People with dementia often show the poor judgment of money, give a lot of money to telephone advertisers or pay for repairs to houses or products they do not need. Problems with abstract thinking; evaluating a test book can be more difficult when the task is more complex than usual. A person with Alzheimer's disease can completely forget what numbers are and what to do with them. Wrong things; anyone can misplace a wallet or key for a while. A person with Alzheimer's disease may put things in an unusual place: an iron in the fridge or a wristwatch on a sugar bowl. Changes in mood or behavior; everyone can be sad or happy from time to time. Someone with Alzheimer's disease may show a rapid change in mood — from calm to tears to anger — for no apparent reason. Personality changes; people's personalities gradually change over the years. But a person with Alzheimer's disease can change drastically, be extremely confused, suspicious, scared, or dependent on a family member. Loss of action; it is not uncommon for tiredness to do housework, business dealings, or sometimes social obligations. A person with Alzheimer's disease may be quiet, sit in front of the TV for hours, sleep more than usual, or do not want to do normal activities. If you notice any warning signs in you or a loved one, consult your doctor. Early diagnosis of Alzheimer's disease or other disorders that cause dementia is an important step in finding appropriate treatment, care, and support services.


Samina Zaheer (Health tips, Health care)

 

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